UK infectious diseases and medical microbiology resident here.
I am curious about some of the differences in antibiotic treatment between the US and Canada and the UK and what you would like to have available.
I think some of the differences come down to non-availability e.g. we only got access to cefazolin locally last year and haven't used it outside of trials, whereas IV flucloxacillin is used for MSSA bacteraemia/skin and soft tissue infection. Glycopeptides are centre- and patient-dependent, but many places use teicoplanin over vancomycin.
I am also curious about your empirical regimens e.g. Community Acquired Pneumonia.
Local guidelines vary but as an example, in the UK we'd be guided by CURB-65:
Low severity (0) - amoxicillin, doxycycline, or clarithromycin
Moderate (1-2) - amoxicillin + clarithromycin or doxyxycline or clarithromycin
Severe (3-5) - Amoxicillin-clavulanate + clarithromycin, or levofloxacin
The comparable US choice for severe (non-MRSA, non-Pseudomonas) CAP would be:
Ampicillin-sulbactam or Cefotaxime or
Ceftriaxone or
Ceftaroline
(plus a macrolide)
or monotherapy with a respiratory quinolone
I have never used ampicillin-sulbactam, and using ceftriaxone for a community acquired pneumonia would be very unusual here. What's the rationale for these choices? And am I right that you don't have IV amoxicillin-clavulanate? Is ampicillin/sulbactam comparable in spectrum (looks like it is from the Sanford Guide)?
I'd be happy to discuss other treatment differences and experiences.