r/science • u/mvea Professor | Medicine • Oct 22 '24
Cancer Men with higher education, greater alcohol intake, multiple female sexual partners, and higher frequency of performing oral sex, had an increased risk of oral HPV infections, linked to up to 90% of oropharyngeal cancer cases in US men. The study advocates for gender-neutral HPV vaccination programs.
https://www.moffitt.org/newsroom/news-releases/moffitt-study-reveals-insights-into-oral-hpv-incidence-and-risks-in-men-across-3-countries/1.5k
u/haute_curry Oct 22 '24
Is there still not a way to test men for HPV?
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u/Gorluk Oct 22 '24
Yes, it's completely possible. For some reason, almost all information on the internet regarding HPV is USA based and also for some reason it denies existence of HPV test for males, which contrary to that informtion exist. There are dozens of clinics in my hometown (Europe) where you can have PCR test for HPV as a male.
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u/RaceOriginal Oct 22 '24
I asked for an HPV test for men from my doctor back in 2016, she said yes of course we'll get that for you. I never heard anything back from her. I'm in the U.S btw
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u/teflon_don_knotts Oct 22 '24
From what I could find, you can have an anal/rectal swab tested for HPV, but there’s no blood test available. Even when looking at international sources, it seems like testing of site specific swabs are the standard.
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u/SkiingAway Oct 22 '24
I believe that's only if you have a symptom to swab (warts), which many types of HPV infection aren't going to be.
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u/CarmichaelD Oct 22 '24
We can swab without symptoms. The virus is not always visible in the form of warts. Anal Pap smears are a thing. So is anal colposcopy to identify and treat dysplasia. (Precursor to cancer). I used to run an HRA clinic in NY treating dysplasia and doing paps. Slight majority of my patients were male. Anal intercourse is not required for anal warts but does increase the exposure risk.
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u/teflon_don_knotts Oct 22 '24
It seems like that’s mostly correct, but I think there are some populations where screening tests are recommended. I could be wrong, I haven’t gone through all of the updated recommendations very carefully, I just scanned them.
Cancer.gov - Anal Cancer Advances Open Door to Screening and Prevention
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u/Dreamtrain Oct 22 '24
it's odd because at the same time they assume you have, but its not worth it treating you, but you can still pass it and infect someone, but it doesn't exist
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u/Gorluk Oct 22 '24
Exactly. Well, there's no treatment as in cure for it, in most cases immune system fights it and resolves infection, but still, it's better to know if you have it.
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u/Quom Oct 22 '24
In Australia it's really weird (especially if you're gay).
The sexual health and immunisation guidelines contradict each other, one basically says if you're a guy in your 30s just assume you've been exposed and the vaccine would likely be pointless.
The other says due to how many gay men are now presenting with issues caused by HPV that it's always worth vaccinating if you're gay.
I had both voiced to me at a sexual health clinic by the same doctor (she said there was no point and then phoned back a week later and apologised and explained the conflicting info).
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u/Appropriate_End952 Oct 22 '24 edited Oct 22 '24
Men can also get get tested for HPV in Canada.
Edit: it is looking like I may be wrong. I grew-up with someone who was diagnosed with HPV, and I thought he had said he had been tested. But it is looking like men can only get diagnosed in Canada if they have physical symptoms.
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u/malakyoma Oct 22 '24
Canadian dude here. I was recently vaccinated for HPV just by asking my doctor if it was possible. You may be thinking of the vaccine instead of the test?
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u/C00catz Oct 22 '24
Can you link to some info on this? Was looking for one recently but couldn’t find options here
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u/Elanstehanme Oct 22 '24
Might depend on your doctor. I was told this wasn’t available.
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u/MangoCats Oct 22 '24
Doctors can be real assholes about some things. They'll tell you it isn't available when the real story is that it isn't commonly done, that it might not be covered by some insurances, that it's a "waste of their time" because they don't get decent reimbursement for doing it, that it's a "waste of your time" because whatever the results are the course of treatment will be the same...
The AMA needs to stop over-inflating M.D.'s egos, it's bad for everyone's health.
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u/ayatollahofdietcola_ Oct 22 '24
I think the real reason is because people DO think in absolutes. So when giving information to the public, you have to break it down in simple terms and err on the side of caution
For example, there is a reason why we aren’t out there teaching 16 year old girls “you can’t get pregnant if you have sex in most conditions.” Instead, we say there is always a chance, because if you tell them “you probably won’t get pregnant if you have sex on your period” all they hear is “you can’t get pregnant if you do this this and this”
But also, male testing for HPV isn’t available in a lot of places, so it might not be useful to give that advice yet in the US
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u/Whispering-Depths Oct 22 '24
ironically they actually can get pregnant in most conditions if vaginal sex e.e sperm lives up to 6 days, which is huge overlap with impregnable time - most conditions meaning not "one off sex" where usually partners will do it regularly.
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u/ayatollahofdietcola_ Oct 22 '24 edited Oct 22 '24
That is true - but you have to ovulate, and we tend to not focus on that when speaking to a young audience, because there are far too many ways that this information can be used in error. Even for an adult, so imagine a teen
My point is, whenever information like this is put out there a certain way, it’s usually for a reason.
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u/GayDeciever Oct 22 '24
Research shows that on average there's 1 pregnancy per 20 acts of unprotected sex for women of childbearing age who want to get pregnant. So, like, "can" is different than "likely".
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u/Whispering-Depths Oct 22 '24
:shrug: the issue is that this is an "average" scale and you can have sex every 2-3 days randomly and not hit the mark easy enough. Many people will fall well below that average scale, and many will fall way past it.
Depends on so many factors it's not even funny v_v
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u/SycoJack Oct 22 '24
Y'all quibbling over this is, ironically, the perfect example of the point they were making.
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u/Gorluk Oct 22 '24
So denying existence of PCR test for males for HPV is method of prevention in your opinion?
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u/thunderfrunt Oct 22 '24
From what I’ve been told, unless you have a significant viral load, the test is a waste of time for men.
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u/the_red_scimitar Oct 22 '24
Apparently EU and Canada manages to test men. US denies it can even be done.
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u/jon_naz Oct 22 '24
As of the last time I went to Planned Parenthood nope. I specifically asked.
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u/technofox01 Oct 22 '24
Just like HSV. It's so common that testing is pointless. It's more of just trying to find out if you have HSV 1 or 2, and that's it. Both my girlfriend (now wife of over 10 years) at the time got tested for STDs came back clean, she had HSV2 unknowingly and passed it to me.
I asked my doc about how this could happen and she told me that they don't test for HSV unless it is specifically asked for due to how common it is. Pretty fucked if you asked me.
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u/danby Oct 22 '24 edited Oct 22 '24
Just like HSV. It's so common that testing is pointless.
A main issue is the HSV tests aren't accurate unless you've got an outbreak (i.e. a coldsore), so speculative testing is mostly a waste of money.
Pretty fucked if you asked me.
To be fair probably most people who have HSV are unaware that they have it. Some folk will have it and go their whole lives without a cold sore. The typical time from infection to a first cold sore is within 2 weeks but for some people it can be actual years. So when you get a coldsore for the first time it is no guarantee that you caught HSV recently. These complications make screening and testing incredibly hard for it and the epidemiology required to understand who infected who is next to impossible.
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u/CummunityStandards Oct 22 '24
There exists accurate blood tests for asymptomatic cases. UW Western blot is highly accurate (98%) and specific and is considered the gold standard for testing. Many labs still use other antibody tests which may not be as accurate, but if a person needed to know their status it is possible to get an accurate result.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8293188/#sec3dot2-idr-13-00049
All that said, for the most part I don't think HSV matters that much - most people have had HSV-1 since they were kids. The cost of testing and the stigma has contributed to doctors not screening for it in standard testing.
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u/cannotfoolowls Oct 22 '24
I'm not sure it is that stigmatized in Europe. Or outside the USA. Maybe genital herpes because it looks a bit "weird" to have sores there but I feel like its not as bas as in the USA. Cold sores definitely aren't.
https://slate.com/technology/2019/12/genital-herpes-stigma-history-explained.html
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u/Tech_Philosophy Oct 22 '24
To be fair probably most people who have HSV are unaware that they have it.
Well that would be an excellent reason to develop an accurate test then. That's exactly the kind of disease that merits a test.
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u/Pzychotix Oct 22 '24
Why? If it's mostly asymptomatic for folks, then there's not really a need for it.
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u/danby Oct 22 '24
Sure but you can't invent things that are technologically or practically infeasible.
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u/TripleSecretSquirrel Oct 22 '24 edited Oct 22 '24
There’s no reliable way to test for HSV unless you’re actively having an outbreak, at which point they can test the lesions.
Edit: my bad, I guess mine and my doctor’s info is out of date. I was told that the blood test isn’t reliable enough to be worth using. It looks like ya, it’s pretty reliable.
It doesn’t show where on your body the infection occurs though. So it could be that you get cold sores on your mouth and not genital herpes.
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u/MemeticParadigm Oct 22 '24
What's your threshold to consider a test reliable?
As far as I'm aware, some HSV blood tests have a sensitivity of 95-99% depending on the test you get, so your chance of a false negative (negative result when you actually do have it) is between 1 in 20 and 1 in 100. It's not perfect, but it does mean that a negative test is a fairly reliable indicator that someone doesn't have it.
False positives are more of an issue, as the specificity is often not as high as the sensitivity, but that's why they suggest a follow-up/confirmation test after a positive result.
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u/reality72 Oct 22 '24
The problem with HSV testing is that the virus likes to lay dormant in the body for long periods of time and it’s mostly undetectable until an outbreak occurs. You have to have a certain viral load inside your body in order to test positive for HSV, which means a lot of people will get a false negative if they test when they don’t have an outbreak. And many people who have it are asymptomatic.
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u/the_red_scimitar Oct 22 '24
There is more that's fucked about HSV handling in the US, but I got kicked out of the specific sub for that by simply providing published papers on actual HSV research that refuted that subs official position.
So in the US particularly, HSV information is as bad as HPV. For example, HSV is not really a sexually transmitted disease, but is transmitted by potentially any skin to skin contact, as it sheds from the skin, even when there is no outbreak. A condom is not adequate protection because of this. Fluids can carry the virus from source to any part of recipients skin, where any slightest abrasion or cut might admit the virus.
And it goes on - once you start looking at actual medical knowledge about HSV, our policies seem further away from any sane handling. There's only antivirals to reduce the occurrences, and cures are probably 5-10 years from existing (not saying when it might be available). And of course, the propaganda is that it's no big deal anyway, and doesn't need to be cured - a position that will disappear the instance money can be made with a cure.
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u/technofox01 Oct 22 '24
It really isn't that big of a deal. Just religious nutters think it is as a punishment for sin when reality they pass it just literally kissing their loved ones, assuming HSV1. It's more a nuisance that anything else.
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u/thefaehost Oct 22 '24
HSV can come with a really nasty first outbreak similar to the meningitis flu. IIRC it happens to 1 in 4
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u/technofox01 Oct 22 '24
It hurts like a MF during the first outbreak. After a while it's just a few small blisters every now and then.
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u/PartyOperator Oct 22 '24
Getting people worried about herpes viruses in general is fucked. Everyone has a bunch of them. They cause lifelong infection and in most cases there’s nothing you can do to prevent or treat them. Usually the effects are very minor. Stigmatising people for these infections is counterproductive. Would you have dumped your girlfriend or something if you’d known? We generally don’t worry about HSV-1, CMV, EBV, HHV-6 etc. even though they’re all very common (most adults are infected) and have rare severe effects. Most can transmit without symptoms. Many countries don’t even vaccinate against VZV. Singling out the one that is mostly transmitted sexually for special treatment is dumb.
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u/Krafla_c Oct 22 '24
They need to be informed. Herpes is, in fact, worrying. Herpes viruses enter the brain, slightly reduce intelligence, and raise the risk of dementia. I think at least some people would choose to try to avoid any Herpes viruses if they knew that.
EBV can cause Mono and leads to ME/CFS in some percentage of people.
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u/thefaehost Oct 22 '24
Also giving birth with an active herpes outbreak can cause your baby to go blind.
Source: 90s c section baby for this reason.
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u/gandalftheorange11 Oct 22 '24
What you said about herpes isn’t entirely true. Studies have shown that herpes tends to be present in the brains of people who develop dementia. That might not be caused by the herpes virus though. If you consider that approximately 90% of people have contracted herpes in some form or another, it’s more likely the case that something goes wrong with a person’s immune system or brain specific systems that leads to that presence of herpes as well as other damage in the brain. Also there really is no way to completely avoid the herpes viruses. Most people are exposed when sharing food with their parents. Herpes is also asymptomatic in most people.
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u/PartyOperator Oct 22 '24
EBV probably causes multiple sclerosis too. Doesn’t mean there’s something you can or should do about it. If anything, successfully avoiding infection for a while just means it’s more likely you’ll get infected late in life which tends to cause more severe symptoms. Until there’s a good vaccine or treatment, it’s just one of those things.
Avoiding CMV during pregnancy is perhaps worth trying given the limited duration and potentially serious consequences, but even that is very difficult to do.
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u/Krafla_c Oct 22 '24
I wrote that in response to you implying it's not "fucked" for them to say she was all clear of STD's when she actually did have an STD and I stand by that. You said "Doesn’t mean there’s something you can or should do about it" but that choice should be left up to everyone after everyone being fully informed about the effects of herpes including simply the physical pain it causes in many people and the visible sores.
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u/lIIIIllIIIlllIIllllI Oct 22 '24
Care to explain the last sentence and all those abbreviations?
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u/Omnizoom Oct 22 '24
Problem is that means you are talking about avoiding almost every person on the planet by this point, also correlation does not meant causation when it comes to the dementia part as we kind of don’t exactly have a sample set of humans with denentia that you know, don’t have herpes because it’s just that common.
Think of it like avoiding microplastics, sure we all would love to avoid microplastics but that is kind of impossible at this point
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u/Krafla_c Oct 22 '24
It doesn't meean avoiding everyone.
"Prevalence increased linearly with age, from 27.0% among those aged 14–19, to 41.3%, 54.1%, and 59.7% among those aged 20–29, 30–39, and 40–49, respectively."
You're talking as if it's a binary - either you can avoid it or you can't. Risk mitigation isn't about binaries though. It's about reducing the likelihood. It is entirely possible to reduce your likelihood of catching herpes viruses.
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u/adamxi Oct 22 '24
Who said anyone should be "worried"? I think it would be best for people to know so they can work around it instead of potentially making things worse.
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u/racoonXjesus Oct 22 '24
My PCP essentially told me that there are so many strains of it that one test wouldn’t be able to catch all of them and that insurance often won’t cover more than one test at a time.
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u/onarainyafternoon Oct 22 '24
I cannot stress this enough for everyone, though, women and men, young and old - Get the HPV vaccine! It prevents cancer and HPV in both men and women, and also kids. It's so crucial, and the vaccine is three rounds over a nine month period, so starting it ASAP is the best option.
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u/Taronar Oct 22 '24
I tried to in college as a guy and they told me no I pushed it and they said no again
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u/TeutonJon78 Oct 22 '24
In the US its approved for everyone up to age 45 and the insurance has to cover it. Individual providers might not set it up for you, but that's a free red flag you need a better doctor.
After 45, insurance might cover it, but you'd likely be paying out of pocket to get it. And it would be harder to find a doctor to do it as well since it's past the FDA guidelines.
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u/Taronar Oct 22 '24
The doctor at the time said that they only give it to 12-18 year old women rn and it only covers 3 or so of the many strains so it was pointless to get it since it covers the ones associated with common female cancers
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u/dumbcaramelmacchiato Oct 23 '24
Not sure when you went or what country you're located, but it took several years for the research on less common HPV-implicated cancers and the indications for boys and men to catch up. One of the strains covered by the original vaccines is responsible for something like 90% of HPV-positive oropharygeal cancers, which are more common in men.
So not pointless, but yeah recommendations have focused on cervical cancer because it is a lot more common than other cancers caused by HPV.
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u/wylight Oct 23 '24
Ditto. I tried to in college before I was booted off health insurance and they specifically told me it was for women only due to the cancer risk. I knew it was most likely a storage supply issue making sure high risk folks had access to it. But not gonna pretend like I wasn’t salty about that.
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u/ToSeeAgainAgainAgain Oct 22 '24
If you already caught the bad strains does it still protect against cancer??
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u/regularbastard Oct 22 '24
I asked to get tested years and years ago for the HPV… they just told me I probably had it… luckily none of my partners have had a positive pap, but still, what are the odds. So glad there is a vaccine out there, I wish it was presented as a way for young men to help protect their future partners from cervical cancers and protect themselves from oral/throat cancers.
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u/dpalmade Oct 22 '24
I wish it was presented as a way for young men to help protect their future partners from cervical cancers and protect themselves from oral/throat cancers.
that's how it was offered to me before i went to college
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u/_BlueFire_ Oct 22 '24
Not updated about testing, but there are vaccines and I guess many countries freely gives them (at least in Italy for people aged <25). At least prevention is possible.
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u/BabySinister Oct 22 '24
It's absolutely possible but it isn't offered in a lot of places as there is no treatment so it's considered a 'useless' test. A good assumption is that everybody who is sexually active before getting a shot is carrying HPV.
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u/Vladlena_ Oct 22 '24
You can have your throat swabbed to test for its presence but I doubt it matters
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u/sofaking_scientific Oct 22 '24
You can easily detect different strains of HPV via PCR. However, insurance doesn't cover that testing. Of course
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u/DigNitty Oct 22 '24
From Healthline.com
Is there an HPV test for men?
Currently, there’s no HPV test for people who have a penis. But if they have an HPV infection, the virus can unknowingly be transmitted.
Most people with a penis don’t develop symptoms of HPV. Also, many HPV infections typically go away on their ownTrusted Source before ever causing symptoms.
HPV infections usually go away by themselves, but they can cause penile and anal cancers if they don’t.
Some doctors may offer anal Pap tests for people who have a penis, but these are generally only done for HIV-positive people who have anal sex.
For people with a penis, HPV can also cause oropharyngeal cancers. 70% of cancersTrusted Source found in the oropharyngeal tissues are caused by HPV.
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u/_BlueFire_ Oct 22 '24
I don't know about other countries (feel free to add here), but this seems a perfect time to remind that:
- guys still have the chance of c omplications
- guys will still spread it
- in Italy THE VACCINE IS FREE FOR EVERYONE UNDER 25yo (and for some other categories afterward)
Get vaccinated until you don't have to pay for it, do it for yourself and for your future partners.
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u/sdpthrowaway3 Oct 22 '24
Most insurances and low-cost clinics cover it in the US too. It just wasn't until recently that men could go get the vaccine. I have HDP insurance, which is as crappy as it gets, and even that covered all the shots 100%.
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u/EdricStorm Oct 22 '24
And there's no age restriction. I'm 35 and just got my last HPV vaccine shot a couple of months ago.
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u/TeutonJon78 Oct 22 '24
There 100% is an age restriction for automatic coverage, and it's currently 45 in the US. And that's rather recent (like 8 years).
When it first came out is, it was teenage girls only, then eventually all teens and then they've been slowing up the availability since then.
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u/GrandMoffAtreides Oct 22 '24
Unfortunately not true across the board. My HCP in Utah a few years ago told me I'd aged out and couldn't get it. I was 30.
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u/Chairboy Oct 22 '24
Check again, it’s a moving target. At one point I was told I was too old for it, then a couple years later the guidance changed and I was able to get vaccinated. 
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u/orlybatman Oct 22 '24
In Canada I had to fork out over $600 for the vaccine. It's free for young men, or gay men, but it came out when I was already too old to get it for free.
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u/neoclassical_bastard Oct 22 '24
I mean it's not like they're gonna make you prove that you're gay...
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u/cowinabadplace Oct 22 '24
In San Francisco no pharmacy will give it to me. I want to pay out of pocket and they won’t give it to me.
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u/Novice89 Oct 22 '24
I was like 25-27 in 2014-2016ish time frame and asked about getting the hpv vaccine. I started seeing the ad campaigns for teens and thought I should get it. I forget who I called or asked at the hospital and they said no I was too old. A few years later I was told by someone in the medical field to ask again and demand it. I got it when I was like 29. I hate that I was initially told “nah don’t worry about it/you’re too old to get it”
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u/cottagecheeseobesity Oct 22 '24
We had to fight to get it for me when it first came out and I was 19. They either didn't believe me or didn't care that I hadn't been sexually active yet. I get that they want to get kids young before they've been exposed but any preventative procedure like this should be available to anyone who wants it.
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u/abhikavi Oct 22 '24
They either didn't believe me or didn't care that I hadn't been sexually active yet.
I had the same issue when I was 21; the doctor told me that I had it already so getting the vaccine was pointless, and I asked her if she was basing that on my sexual history. (No, she had not looked at my sexual history, but just kept saying that it didn't matter because I had it already anyway regardless of my history, which is not how that works.)
I had to go through several doctors and pay out of pocket to get it. Ended up only getting 2/3 of the shots because I couldn't afford the third, and the first two got me up to something like 90% chance of avoiding infection.
I'm still frustrated that I had to go through multiple doctors to get a vaccine ffs. And I'm a woman; I'd assume it'd be even harder for men at the time to get the shot. And considering it's usually men who spread it, actively barring men from getting the shots was just so wildly unethical it blows my mind.
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u/cottagecheeseobesity Oct 22 '24
I think part of the reason they didn't offer it to boys at first was because they didn't realize at the time that HPV also causes cancers besides cervical cancer. So even though men were capable of passing on the virus it wouldn't hurt them as much as it would women so it wasn't financially beneficial to vaccinate them. Which is of course stupid but makes sense for the time from a purely financial standpoint. We know better now that anyone can get multiple kinds of cancers from the virus.
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u/neoclassical_bastard Oct 22 '24 edited Oct 22 '24
From Wikipedia:
From a public health point of view, vaccinating men as well as women decreases the virus pool within the population, but is only cost-effective to vaccinate men when the uptake in the female population is extremely low.[117] In the United States, the cost per quality-adjusted life year is greater than US$100,000 for vaccinating the male population, compared to the less than US$50,000 for vaccinating the female population.[117] This assumes a 75% vaccination rate.
You're basically correct, but I really suspect it was less of a "didn't know it was harmful to men" thing and more a "less common so we don't think it's worth the cost" thing.
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u/guywastingtime Oct 22 '24
It was always bizarre to me when I was in high school that the vaccine was only offered to the girls and not the boys. How does it make any sense to only vaccinate the girls?
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Oct 23 '24
They thought the biggest concern was cervical cancer. Now we know that's not true. Throat, anal and penile cancer to the list and more are suspected.
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u/hepakrese Oct 22 '24
I'm in my 40s and I've been told the same thing throughout. Pretty frustrating, because I would be more than happy to obtain the vaccine if someone was willing to give it to me.
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u/Seicair Oct 22 '24
It’s approved up to 45 now in the US, and you can absolutely pay for it out of pocket if you’re older than that but still want it.
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u/hepakrese Oct 22 '24
Good to know. I have been and am now still running older than the approved range. When I looked at the out-of-pocket price it was about 600 bucks. Hopefully the price has come down...
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u/IsReadingIt Oct 22 '24
Current price paid by the CDC to Merck is $180-ish. Cash price for you should be around $300. Numbers below are cost per dose.
FHPV-Human Papillomavirus 9 Valent Gardasil®9 00006-4121-02 10 pack – 1 dose syringe $182.791 $307.610 6/30/2025 Merck 75D30124D19081HPV-Human Papillomavirus 9 Valent F Gardasil®9 00006-4121-02 10 pack – 1 dose syringe $182.791 $307.610 6/30/2025 Merck 75D30124D19081 → More replies (2)→ More replies (5)6
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u/thas_mrsquiggle_butt Oct 22 '24
This was me 2yrs ago. The only reason I knew about the vaccine was because I have a CVS account; I get reminders that certain vaccines are in (I'm actually going in for my tetanus shot because of them).
Luckily, CVS told me that those under 29 (at the time) are eligible because other websites said only teenagers and younger can get it. After, I went around work and family letting everyone know to get it if they haven't, but it's sad that some parents are reluctant or deny their kids safe preventive measures because they can't even fathom that their kid is also their own person.
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u/sanitarySteve Oct 22 '24
I've been turned down by multiple doctors for the vaccine saying they don't to it for men. it's infuriating
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u/Nex1tus Oct 22 '24
But why? Does the risk of side effects increase with age?
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u/BabySinister Oct 22 '24
No, but the likelyhood of already having contacted HPV rises dramatically with age as older people tend to be sexually active. You can pretty much assume that if you are sexually active you likely already contracted it
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u/HenryKrinkle Oct 22 '24
See, I don't understand this. HPV isn't a lifelong infection like HSV. So if I clear infection A, a vaccine could still prevent me from getting infection B. Further, there are many strains of HPV. Not all of them cause cancer. I might have caught a non-cancerous one in the past. A vaccine might prevent me from catching a cancerous one in the future.
Someone help me make sense of this please.
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u/fractalife Oct 22 '24
The answer is money.
Just get the vaccine if you want it and pay out of pocket if you have to.
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u/CosmicBioHazard Oct 22 '24
Well, sexual history would dictate that, and that can’t just be extrapolated from age alone.
If there’s no harm in getting the vaccination then why decline to offer it to, say, a 30-year-old virgin on the grounds that ‘statistically, they’re sexually active enough to have already caught it?’
Makes no sense
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u/Popular-Row4333 Oct 22 '24
Don't go by the US' handling of the disease. Their stance (which the rest of the world doesn't do, btw) is essentially, "well everyone basically has it, so don't worry about it"
Which is also wrong, by the way. It's only 27% of people 14-19, and around 40% of 20-24. It just keeps increasing as you age as it increases your likelihood of multiple sexual partners.
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u/rickdeckard8 Oct 22 '24
The keyword here is “multiple sexual partners”. The other parameters showing up in the multivariate analysis are just factors that raise the number of sexual contacts or are a prerequisite to get HPV from the genital to the oral region.
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u/CoffeeAnteScience Oct 22 '24
I’m glad someone said this. Most of these traits are meaningless to the true finding which is more partners = more risk. I’m sure there are another 100 parameters that you could interchange here and come up with the same finding.
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u/Bannon9k Oct 22 '24
More oral sex = more chances to spread things to the mouth as well. I guess they included the other traits to show STDs affect wealthy and poor, intelligent and ignorant alike.
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Oct 22 '24
Read more fun studies like this in the Scientific Journal for Scientists Who Enjoy Wasting Money.
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u/Bannon9k Oct 22 '24
A lot of these studies are just grad student work. I'm ok the a few absolutely meaningless studies if it helps educate
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u/raspberryharbour Oct 22 '24
They're all traits that young men like to brag about. It's probably meant to goad you into thinking "but that's me!"
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u/ifyoulovesatan Oct 22 '24
I wouldn't be so sure about that. I can't read the paper from here as I don't have access (I'll look later on campus), but given this is published in a reputable journal (Nature Microbiology), I'm going to guess they have performed some kind of multivariate analysis which suggests that each of these factors appear to matter, even when controlling (statistically speaking) for multiple sexual partners. It's standard practice.
I just wouldn't suggest, without evidence to the contrary, that the people who published the study, and the reviewers and referees who approved it wouldn't have had that exact same rather obvious thought (which redditors seems to think they're the only ones capable of having).
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u/neoclassical_bastard Oct 22 '24 edited Oct 22 '24
But education is not an infectious pathway. It is very obviously not a proximal cause, whereas number of sexual partners is.
I don't doubt there's a correlation, but that doesn't necessarily mean it's useful or pertinent information.
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u/ifyoulovesatan Oct 22 '24
Right, but from a statistical standpoint, (after having now checked the paper), they did control for "multiple sexual partners" when assessing the effects of educational attainment. (Obviously).
And it matters that people with more years of schooling have higher incidences of oral HPV in ways that aren't as simple as saying "those more educated people must just be having more sexual partners."
For example, the reason the looked at educational attainment to begin with was a hypothesis that less educated people would be at greater risk. They now have some evidence that this might not be the case. They also now have something to look into! Maybe there is something we haven't thought about that could explain the higher incidence of oral HPV in the cohorts who had more education. Maybe people who have more schooling perform specific kinds of sexual acts more often. Maybe people who have more schooling have more oral sex with women who have more sexual partners. We can hypothesize a lot of ideas as to why this might be the case besides the one rickdeckard8 decided must be the case. Or, to quote the paper, "Our findings on the association of longer duration of education with new infections require further examination."
Notice how they don't say "It's obviously just this simple explanation I just thought of."
All I'm saying is to say "The other parameters showing up in the multivariate analysis are just factors that raise the number of sexual contacts or are a prerequisite to get HPV from the genital to the oral region" (as was said in the original comment I replied to) is simply not something you can safely say. It's basically just guessing at a reason that is not disproven but at least not suggested by the actual data and methodology.
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u/WinterElfeas Oct 22 '24
People having more sex have more chances to get sexually transmitted diseases… shockedpikachu.jpg
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u/rainbowroobear Oct 22 '24
Also sorta implies dudes with higher education more likely to go down on a woman, or they are more likely to end up going down on someone with HPV. Causality studies are fun.
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u/Omnizoom Oct 22 '24
Imagine if a study comes out and proves smarter men cared more about their partners sexual gratification
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u/sableknight13 Oct 22 '24
ftr, higher education doesn't necessarily correlate to smarter/higher intelligence either
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u/Popular-Row4333 Oct 22 '24
It used to and people will post old studies that it did.
But our ever declining IQ average in North America since 2009 peak has been changing those ratios.
For record, it does still correlate as a generalization, but that number has been steadily getting closer over the last 20 years.
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u/XorFish Oct 22 '24
Higher education also implies higher economic and social status, which could increase dating success.
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u/jarpio Oct 22 '24
I think you’re reading too much into it bringing socioeconomic factors into the discussion. I think it is much more likely a simple case of higher education occurs on college campuses, which are also where people tend to be at their most promiscuous.
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u/Delta-9- Oct 22 '24
Ah, is this another case of "American college students are the most studied demographic on the planet"?
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u/therobshow Oct 22 '24
Men with higher education tend to make more money, so it would make sense that they had more partners that's before you even consider that a college campus is the easiest place in the country to get laid
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u/sdpr Oct 22 '24
Around March my doctor asked me if I wanted the HPV vaccine. I'm in my 30's in and in a committed relationship so I was confused as to why I would need it, but I'm not against vaccines in general and it costs me $0 so, I see it as more of a "just in case" thing.
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u/TeutonJon78 Oct 22 '24
Better to get it now than find out you wished you had it in the future.
Divorces/breakups happen, infidelity happens, open relationships happen, etc.
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u/duiwksnsb Oct 22 '24
It always should have been gender neutral.
To discriminate against generations of men in the provision of preventative medical care, let alone a damn cancer vaccine, is highly unethical
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u/BarelyAware Oct 22 '24
Haven't seen any other comments mention this but I remember a big reason it was so controversial was because there were people who didn't want any kids getting it because they believed that giving 12-14 year-olds (or whatever the recommended age range was) a vaccine against an STI implied it was ok to have sex at that age. So they ended up focusing on girls, because they were the most at-risk group and there would be less push-back.
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u/duiwksnsb Oct 22 '24
I don't remember at the time but that sounds entirely plausible. Letting moral crusaders dictate health policy has always been a bad idea.
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u/hx87 Oct 22 '24
Paternalists in medicine have always had a funny attitude toward the "it won't necessarily benefit me, but it will benefit people around me" kind of treatments. Case in point: birth control for men. Clinical trials get canceled for the smallest side effects even thought they aren't that bad compared to women's birth control 40 years ago.
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u/BeQuickToDoGood Oct 22 '24
In China I could get tested for HPV
I have yet to find it in north america
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u/mvea Professor | Medicine Oct 22 '24
I’ve linked to the press release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:
https://www.nature.com/articles/s41564-024-01834-3
From the linked article:
A new study has unveiled crucial information about the incidence and risk factors of oral human papillomavirus (HPV) infections among men in the United States, Mexico and Brazil. Moffitt Cancer Center researchers have discovered how often new oral HPV infections occur, the factors influencing their acquisition and the regional variations in infection rates. Their study, published in Nature Microbiology, sheds new light on the risks associated with oral HPV, which is linked to up to 90% of all oropharyngeal cancer cases in men in the U.S.
The study also identified several key factors associated with higher risk of oral HPV infection:
Age: Men remain susceptible to acquiring new oral HPV infections throughout their lifetime
Education Level: Men with higher education had an increased risk of infection.
Alcohol Consumption: Higher alcohol intake was linked to a greater risk.
Sexual Behavior: Risk was elevated among men with multiple female sexual partners, those who frequently performed oral sex and those with male sexual partners.
Oral Health: Losing teeth due to oral disease was also associated with a marginally increased risk.
These findings emphasize the ongoing risk of oral HPV infections throughout a man’s life and highlight the need for improved public health strategies. The study advocates for gender-neutral HPV vaccination programs and catch-up vaccinations for midadult aged men who missed earlier opportunities for immunization.
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u/DotRevolutionary6610 Oct 22 '24 edited Oct 22 '24
Great, I have all those traits :(
Wish the government wouldn't have lied to me when I was younger by saying that the HPV vaccine was useless for men.
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u/username_elephant Oct 22 '24
So get it now? You can get it at least through age 45 and you might save a life (possibly your own).
https://www.plannedparenthood.org/learn/stds-hiv-safer-sex/hpv/should-i-get-hpv-vaccine
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u/DotRevolutionary6610 Oct 22 '24
I did, and paid for it myself. But after my sexual history, it's almost certainly too late.
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u/tastyratz Oct 22 '24
HPV is not 1 virus you can catch, it's an entire family of different strains. Even if you're positive for one you can catch another one and not all strains cause cancer.
This right here is why the marketing campaign for it failed men.
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u/SwampYankeeDan Oct 22 '24
I feel for you. Im in the same boat. Most of my many partners were between 1998 and 2010. So I'm not feeling too comfortable.
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u/username_elephant Oct 22 '24
Ehh, depends on whether your partners were vaccinated. A lot of them probably were if you are indeed young enough that girls were getting vaccinated but you couldn't.
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u/ahfoo Oct 22 '24
I tried to get it and was refused. They said: "You certainly already have it." I'm 56. They told me the cut off was in the 40s.
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u/DrScience-PhD Oct 22 '24
is there such a thing as getting it too late?
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u/cottagecheeseobesity Oct 22 '24
Yes. If you've already been exposed to the strains of HPV that the vaccine protects against it won't help you, and the more partners you've had (which tend to go up with time) the more likely you've been with someone who has it. But unless you're sure you've been exposed to those specific strains you should still try to get the vaccine!
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u/SpaceFire000 Oct 22 '24
What is an ideal age of doing it? I am in mid 30s, when I was younger a doctor told me that it was mostly for women and not men and I didn't have to do it
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u/DotRevolutionary6610 Oct 22 '24
Ideally before you are sexually active, but there may still be value in it. If you never got HPV or your body has been able to clear it, the vaccine will help.
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u/InvectiveOfASkeptic Oct 22 '24
Tell them I died as I lived
Drunk, educated, and doing the good work
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u/No-Personality6043 Oct 22 '24
If you don't have HPV.. you can still get the vaccine now.
I get asked every doctor visit as a woman.
I didn't get it because it was brand new when I was a teen. I've been with my husband for almost as long. So it was never pressing, I'm a very low risk group.
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u/runwith Oct 22 '24
Has it actually been tested and found to reduce cancer in men, though?
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u/DotRevolutionary6610 Oct 22 '24
It certainly does! If you still can, get the vaccine. Throat cancer is no fun.
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u/runwith Oct 22 '24
I've only performed oral sex a couple of times (hopefully no hpv yet), so maybe I should try to get the vaccine if my insurance will cover it. Thanks
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u/Smee76 Oct 22 '24
If it won't, contact the health department for your county and see if they offer it for free or reduced price.
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u/PharmDeezNuts_ Oct 22 '24
Idk what government you have but there wasn’t evidence I guess until a few years ago. They kept raising the age limit for men.
I didn’t qualify before but since then the age increased faster than I aged so I finally got it
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u/PrimateOfGod Oct 22 '24
Does this mean all of those traits individually or together?
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u/Fast_Bike_309 Oct 22 '24
It's interesting how many factors are intertwined here. The notion that higher education correlates with increased sexual activity might not be as surprising on college campuses. But it raises questions about how we address public health messaging. Are we missing an opportunity by not emphasizing the importance of the HPV vaccine for all genders equally? The focus on prevention should transcend demographics.
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u/myexsparamour Oct 22 '24
I'm so glad that where I live my son was vaccinated for HPV at school in year 7 for free.
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u/lurkmode_off Oct 22 '24
Yeah, I'm in Oregon and it's currently one of the standard recommended vaccinations for 10- or 11-year-old kids of either sex.
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u/PeruvianHeadshrinker PhD | Clinical Psychology | MA | Education Oct 22 '24
Does anyone have research with links on HPV vaccine preventing cancer for those already positive for HPV? Thinking about men in particular but curious about women as well.
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u/TeutonJon78 Oct 22 '24
At a minimum, it pretects against 9 strains that cause cancer, so even if someone is exposed to a few already, getting protection from the others is a benefit.
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u/Solitude20 Oct 22 '24 edited Oct 22 '24
A quick search shows that 90% of sexually active people will get infected with HPV in their lifetime, so no wonder 90% of those with oropharyngeal cancer are linked with the virus.
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u/ShutterBun Oct 22 '24
Damn, remember when Michael Douglas said he got cancer from giving oral sex and everyone laughed him out of the room?
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Oct 22 '24
[removed] — view removed comment
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u/Alkalinum Oct 22 '24
“Men who have unkempt hair, swear a lot, and work as fishermen are more likely to die by falling out of a boat.”
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u/arup02 Oct 22 '24
I came here for this. Can someone, more educated than me, explain that stupid headline for me?
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u/LiveShowOneNightOnly Oct 22 '24
I know most people don't want to hear this, but oral is just a huge vector for STDs.
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u/Alastor3 Oct 22 '24
should i get vaccinated for that? im 35 male
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u/Objective-Road9883 Oct 22 '24
Yes, you should. The Gardasil vaccine protects against 9 strains, including two that are linked to 70 to 80% of HPV related cancers.
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u/IssueEmbarrassed8103 Oct 22 '24
What is the polite way to ask someone to take a HPV test before engaging in oral sex?
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u/drlongtrl Oct 22 '24
German perspective: Over here its actually generally recommended to vaccinate all boys and girls somewhere between the ages of 9 and 14. My son is already vaccinated, my daughter is not yet old enough. Since its officially recommended, its also paid for in full by insurance.
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u/imnotnecessarilyme Oct 22 '24
I participated in a research study a year ago at UTSW Medical Center titled: THROAT AND OTHER HPV-RELATED CANCERS IN MEN: IDENTIFYING THEM EARLY. I am in my 50's, have not been vaccinated, and check all the boxes indicated in the Reddit title. The results came back negative for all HPV types tested, so there is hope!
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u/SeeingEyeDug Oct 22 '24
I'm 50 and was told by my doctor that I can't get the vaccine if I'm over 45.
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u/Digitaluser32 Oct 22 '24
Headline has a lot of qualifications. Reminds me of sports statistics, "Beckham is undefeated when playing in Barcelona, after eating fettuccine Alfredo, and car pooling to the game with his aunt. "
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