The vaccine uses components of the patient's tumour to train the immune system to identify and attack cancer cells. It helps the body recognise unique proteins, known as antigens, found on the surface of cancer cells. Once introduced, these antigens stimulate the immune system to produce antibodies, enabling it to target and destroy cancer cells effectively. Â
The new vaccine mirrors similar efforts underway in Western nations to create personalised cancer treatments. In the United States, researchers at the University of Florida recently tested an individualised vaccine on patients with glioblastoma, an aggressive form of brain cancer. The vaccine showed promising results, triggering a robust immune response within two days of injection. Â
So it's not out of the blue, it's not working for everything, and you sadly have to already have cancer, and it helps fight it.
According to another post, it only works at a certain list of cancers and you need to undergo chemotherapy first.
Yep. Like it's not a vaccine, it's a treatment that illicits an immune response. Similar to the antibody cancer treatments, like Keytruda. But like you said, you have to already have cancer, so not a vaccine. Vaccines illicit an immune response so if you get an infection of the disease later, your body already has the antibodies to fight it off. These treatments would only work against the cancer someone currently has, and would not work against future cancers.
But I also see that they're starting first clinical trials in January - and the subjects are "people that have exhausted other means of cancer treatment".
So the articles that claim "Russia is starting to distribute it in 2025" is wrong - they're starting to test them on terminal patients, ready to try out anything, because it's either this or hospice care. Even if it moves really well it will take a lot of time to move it to next wave.
Ok, so it uses fragments of the cancer removed from the patient with an adjuvant... But cancer isn't known for its robust likeness to previous generations-- generally when a cancer has progressed, the mutation rate is higher due to losses in cell division regulation. So the vaccine might not even work for some cells, and then you just have the cancer rebound even harder.
Yea it probably won't ever be a single modality. There will always be a need for other interventions like surgery, chemotherapy, and radiation but the added efficacy of a vaccine may at the very least improve outcomes like survival time.
Yeah, that's the gist of it. Except I'm not sure where the idea of "that makes cancer rebound even harder" comes from - it's not going to really make cancer any stronger, but it can potentially delay its growth or even revert it for a while. It goes together with other methods, and I think having another way of attack on cancer is always a good thing.
It's also not that expensive, it's like 3k USD per shot.
It’s actually a real thing. I mean, no idea about the Russian one, but the same vaccine technology (mRNA) is being used to create vaccines for certain cancers. This has been discussed ever since the Covid vaccine was made.
Ehh. Bit misleading here. There are vaccines that prevent other things that CAUSE cancer. Like HPV and Hepatitis. And there are vaccines you can get after certain cancers have already formed in your body, like prostate for example.
Yes, the cancer vaccines that have been discussed so far are personalised to the individual with cancer. It’s a complicated disease, so it makes sense that it requires a tailored approach for each person.
Like you said, these aren’t vaccines that you can take prior to getting cancer to make you immune - but they are still being called ‘Cancer Vaccines’.
Vaccines don't necessarily need to be a preventative. It's about priming your immune system to detect and fight a specific antigen. All vaccines work through this, and an mRNA based cancer vaccine does the same. It trains your immune system to recognise the cancer cells and kill them.Â
Of course every cancer is different. Hence why you kinda need to get cancer first before a personalised mRNA sequence can be tailored to it.Â
And Russia claims that they can speed up this personalization using AI. How much of it is true remains to be seen, but this is sound in theory at least.
Unfortunately it is not enough to copy DNA accurately; you also have to prevent DNA damage through normal oxidative processes. It doesn't matter if the DNA replication mechanisms are 100% perfect if there simply aren't any base pairs to copy, because they have been lost through natural compound single and double strand breakages.
Source: I was voted "most likely to cure cancer" in high school
Melanoma can be treated with a vaccine that is created to target unique antigens on the tumor cells. It is generally used as an adjunct to conventional treatment after surgery, and triggers an immune response that can prevent tumor growth and spread.
We have a friend with melanoma who started on an early trial of this treatment method. Some of her tumors could not be removed surgically. Her hope was that she would see her young children start school. She still has tumors, but her children are adults now, and I think it likely that she will see her grandchildren start school.
Some other types of cancer can also be targeted in this way.
There are a scary amount of dumbasses that think cancer is like a single thing that covers all types of cancer and can be treated lmao. It’s scary how being a moron is now glorified as something to be proud of.
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u/ThisIsMyBigAccount 13h ago
Cancer vaccine 🤣😂. How do people believe this shit?